2007, Vol 2 No 2, Article 18
Comparative Efficacy of Two Preparations of Albendazole
against Natural Gastro Intestinal Strongyle Infestation of
Sheep in Kashmir Valley
S. Nasreen, Syed Ghulam Jeelani and Nazir Ahmad Sheikh
A study of the comparative efficacy of two preparations of albendazole against gastrointestinal strongyles in sheep was conducted. The eggs per gram (EPG) values were recorded pre and post treatment and percentile reduction for the two formulations were compared.
Albendazole, Micronized Albendazole, Strongyle, Sheep
The practice of sheep grazing in open post-harvest paddy fields and alpine pastures of Kashmir valley results in heavy nematode infestation. Such infestations lead to high morbidity and low productivity in the affected animals. The seasonal migration of sheep also plays an important role in further dissemination of nematode eggs and larvae. Periodic anthelmintic dosing under such conditions becomes a necessity. Different formulations of the same drugs may affect its efficacy and some manufacturers claim better results with their formulation. In the present trial the results of comparative efficacy of albendazole and micronized albendazole against natural gastrointestinal strongyle infestation are reported.
MATERIALS AND METHODS
Thirty sheep of either sex infected naturally with gastrointestinal
strongyles were selected from Burzahama and Zakura area of District
Srinagar. These animals were randomly divided into three groups A,
B, and C. Group A animal were administered no anthelmintic and
acted as control. Group B animals were treated with a regular
albendazole suspension and Group C animals with micronized
albendazole, both administered orally at the same dose rate of 7.5
mg/ kg body weight.
RESULTS AND DISCUSSIONS
In the untreated control animals (Group A) the strongyle EPG values
showed a steady increase in count from day 0 to day 21. In groups
B and C the EPG count values showed reduction which continued
from day 7 to 21st post treatment (Table 1)
The authors express their thanks to the Director and Deputy Director-Research, Sheep Husbandry Department for providing the necessary facilities. Assistance rendered by laboratory staff is also acknowledged.
Percent reduction of fecal EPG of strongyle specie with two preparations of albendazole
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